Processes
Most work can be viewed as a process.
With most work, there are people problems, and there are process problems.
Process problems always cause people problems. On the other hand, people will often set out to defeat processes, especially if those processes have problems.
As work becomes more complex, especially in the knowledge work field, simplifying the process so that it has no problems is a lofty goal. Once that is done, bring in the artificial intelligence. But there will always be problems for people to solve. In these early days, even AI will likely have problems to be solved.